2008. Precautionary Statements. Synonyms & Trade Names . Bulk Method Last Updated Date : 12/17/2020 The EPA's review relied on toxicology studies performed by the NTP published in 1989 [8]. First-aid measures General AdviceIf symptoms persist, call a physician. This compound is a component of the fluid mixtures used in electronic cigarettes (it enhances the flavour). 1 (800) 239-5288; Customer Support . . Safety evaluation of certain food additives and contaminants prepared by the fifty-seventh meeting of the Joint FAO/WHO Expert Committee on Food Additives (JECFA). FIRST AID MEASURES General advice Consult a physician. . Policies. In vitro studies indicate benzyl alcohol inhibits closure of louse respiratory spiracles, which allows the lotion vehicle to obstruct the spiracles . Exposure Routes inhalation, ingestion, skin and/or eye contact . Final report on the safety assessment of benzyl alcohol, benzoic acid, and sodium benzoate. Benzyl alcohol reacts with triethyl phosphite and zinc iodide to form the corresponding phosphonates. Isoamyl benzyl ether. Benzyl alcohol is a naturally ocurring and synthetic ingredient used as solvent and preservative; has been associated with contact allergy. Even though the product contains preservatives, microbial growth is still possible and it is not an antimicrobially preserved product under USP standards. In case of skin contact Benzyl alcohol is a naturally ocurring and synthetic ingredient used as solvent and preservative; has been associated with contact allergy. Technical grade Benzyl Alcohol (BOH), Assay of 99.6% Minimum, is a clear, colorless liquid with reactive methylene and nuclear hydrogen groups. HHS Vulnerability Disclosure. National Institute for Occupational Safety and Health. National Institutes of Health. Benzyl Alcohol is an organic alcohol found in many fruits and teas. It is a useful solvent due to its polarity, low toxicity, and low vapor pressure. IDENTIFICATION Product Name: INCI Name: CAS#: Product Form: Product Use: Distributor: Address: Telephone: Website: Email: Benzylalcohol-DHA Benzyl alcohol, Dehydroacetic Acid, Water 100-51-6, 520-45-6, 7732-18-5 Liquid Cosmetic use Avena Lab, Farmadria d.o.o. jimmy choo trainers diamond; benzyl alcohol as a preservative in cosmetics; September 29, 2022; beautifeye ingredient; best iceless wine chiller; It is a colorless liquid with a mild, sweet, floral smell. Environmental: If released to soil, benzyl alcohol is expected to display high mobility and readily leach through soil. This position was based on a previous positio n given by EPA (the US Environmental Agency) in 1989 [4]. The Cosmetic Ingredient Review Expert Panel previously established concentration limits for benzyl alcohol, benzoic acid, and sodium benzoate in cosmetics and determined that the available data were insufficient to support the safety of these ingredients during inhalation exposure. Page 1 of 8 MSDS t Benzyl Alcohol Material Safety Data Sheet - Benzyl alcohol Section 1: Chemical Product and Company Identification Product Name : Benzyl alcohol Catalog Codes : SLB3328, SLB4828, SLB2491 CAS# : 100 -51 -6 RTECS : DN3150000 TSCA : TSCA 8(b) inventory: Benzyl alcohol . Even back in the 1920s! Who should use it: In general, benzyl alcohol is safe to use by anyone who does not have a true contact allergy to it. Common antimicrobial agents include chlorbutol, benzyl alcohol, sodium benzoate, sorbic acid, phenol, thimerosal, parabens, and benzalkonium chloride. Benzyl alcohol, benzoic acid and its salts (ie, sodium, calcium, magnesium, and potassium benzoate), and benzyl benzoate are reported to function as fragrance ingredients, pesticides, pH adjusters, preservatives, solvents, and/or viscosity decreasing agents in cosmetic products. Name matches: hypersensitivity benzyl alcohol. Wear chemical splash goggles and chemical resistant clothing such as gloves and aprons. NIOSH Pocket Guide to Chemical Hazards . Department of Health and Human Services. Substance/mixture : The safety of Benzyl Alcohol, Benzoic Acid, Sodium Benzoate, Calcium Benzoate, Potassium Benzoate and Benzyl Benzoate has been assessed by the Cosmetic Ingredient Review (CIR) Expert Panel. published CIR final report on benzyl alcohol, benzoic acid, and sodium benzoate (finalrep, in pdf). Hydrolyzes in H 2 O to benzyl alcohol.] March 2019 Molecular Weight. LOW Cancer HIGH Allergies & Immunotoxicity LOW Developmental and Reproductive Toxicity MODERATE Use Restrictions Ingredient concerns CONCERNS Hospira, Inc., a Pfizer company, is voluntarily recalling one lot of Propofol Injectable Emulsion, USP (containing benzyl alcohol) to the user level due to a visible particulate observed in a . Safety Data Sheet for Benzyl alcohol 102695 Material Safety Data Sheet or SDS for Benzyl alcohol 102695 from Merck for download or viewing in the browser. benzyl alcohol as a preservative in cosmetics. Used to make other chemicals. '5 Final Report on the Safety Assessment of Cetearyl Alcohol, Cetyl Alcohol, Isostearyl Alcohol, Myristyl Alcohol, and Behenyl Alcohol', International Journal of Toxicology. Pictograms. Benzyl alcohol helps to prevent the growth of bacteria that may be introduced through the air or through contamination through use. At levels of 3% or higher, benzyl alcohol has been found to be a skin irritant. As a primary alcohol, it has a mild aromatic odor and is hygroscopic and sensitive to air. Tested to withstand exposure to Acetone, Dichloromethane, Hydrofluoric Acid, and other tough chemicals and solvents. Furthermore, the safety of benzyl alcohol, BA, and sodium benzoate in cosmetics was investigated (Johnson et al., 2017). Benzyl alcohol is a colorless liquid with a mild pleasant aromatic odor. Avoid contact with acids, iron, zinc, aluminum and strong oxidizing agents. Sodium Benzoate, Calcium Benzoate and Potassium Benzoate are salts of Benzoic Acid. . National Center for Biotechnology Information. Safety Data Sheet according to 29CFR1910/1200 and GHS Rev. Description. 8600 Rockville Pike, Bethesda, MD, 20894 USA. May be slightly toxic by ingestion. 1 In 2001, the Cosmetic Ingredient Review (CIR) published a final report on the safety assessment of benzyl alcohol . P261 - P264 - P270 - P301 + P312 - P304 + P340 + P312 - P305 . Benzyl alcohol 100-51-6 >95 4. Classification and Labelling: Chemicals: Annex VI of Directive 67/548/EEC through the 31st ATP. After reviewing the draft report, the Expert Panel needs to determine whether the data included in this report are sufficient for evaluating the safety of benzyl alcohol, benzoic acid, and its salts and ester in cosmetic products. Hazards What is this information? Sodium metabisulfite or benzyl alcohol is added to the propofol to retardthe rate of microbial growth. Find patient medical information for benzyl alcohol topical on WebMD including its uses, side effects and safety, interactions, pictures, warnings and user ratings. Benzoic Acid is an aromatic acid used in a wide variety of cosmetics as a pH adjuster and preservative. 100 mL in Sure/Seal 1, 61, 2 L in Sure/Seal Safety Information. 3 Effective date : 01.19.2015 Page 4 of 7 Benzyl Alcohol Created by Global Safety Management, Inc. -Tel: 1-813-435-5161 - www.gsmsds.com Control Parameters: 100-51-6, Benzyl alcohol , TWA 10.000000 ppm USA. Benzyl ether. Benzyl n-butyl ether. Benzyl Alcohol is metabolized to Benzoic Acid, which reacts with glycine and excreted as hippuric acid in the human . Common Adverse Effects. Contact. (Eye protection must meet the standards in accordance with EN166, ANSI Z87.1 or international equivalent.) Heroja Pinkija 44, Vrac National Technical Information Service. Benzyl Alcohol has a hydroxyl group (-OH), while the related compound, Benzoic Acid has a carboxyl group (-COOH). Benzyl salicylate is one of the first skincare ingredients to help protect the skin from UV rates. b-Isopropoxypropionitrile. Geogard ECT is a preservative that is composed of Benzyl Alcohol, Salicylic Acid, Glycerine, and Sorbic Acid. p-Di-n-butoxybenzene. Keywords: Excipients, package leaflet, benzyl alcohol: Description: This document supports the revision of the annex to the European Commission guideline on 'Excipients in the labelling and package leaflet of medicinal products for human use' with regard to benzyl alcohol. JP - Related Substances - Total other peaks >RT of benzyl alcohol: 0.2 %: JP - Peroxide Value: 5: JP - Residue on Evaporation: 0.05 %: . Benzyl alcohol is an organic compound with the chemical formula C 6 H 5 CH 2 OH. The Company reserves the right to take any action it deems necessary to protect the personal safety of users of this Web Site and the public; however, the Company has no liability or responsibility . Benzyl alcohol can serve as a dielectric solvent for the . It's the esterification of salicylic acid with benzyl alcohol. FOIA. Flash point 194F. 1A (H360D) STOT RE 2 (H373) . Benzyl alcohol induces a reversible fragmentation of the Golgi apparatus and inhibits membrane trafficking between endosomes and the trans-Golgi network. Volatilization from dry soil to the atmosphere may be an important fate process; however, it is not expected to be an important process in moist soils. C 6 H 5 CH 2 OH is a precursor to several esters. Benzyl alcohol is a colorless liquid that has a mild, pleasant aromatic scent. Slightly denser than water. Eyes: Wear safety glasses or goggles if eye contact is possible. Benzyl alcohol | Cosmetic Ingredient Review, Benzyl alcohol, Panel Books, Most Recent Panel Meeting, 161st Expert Panel Meeting, Jun 16, 2022 - Jun 17, 2022, 1620 L St NW Suite 1200, Washington DC 20036-4702, The store will not work correctly in the case when cookies are disabled. Related Pages. Benzyl Alcohol MSDS # 95.00 Section 1: Product and Company Identification Benzyl Alcohol Synonyms/General Names: Benzenemethanol . has reviewed the data on benzyl alcohol in 2002 [10] and has added benzyl alcohol to the ADI group of 0-5 mg/kg bw. Nair B. Benzyl Alcohol (CAS 100-51-6) GHS Chemical Container Label, Dependable 3M adhesive vinyl that is built to resist harsh conditions. Sodium Benzoate is the sodium salt of Benzoic Acid used as a preservative, also in a wide range of cosmetic product types. Benzyl alcohol is stable under normal conditions of use but decomposes with prolonged exposureto air and light. Benzyl alcohol will degrade some plastics, particularly at higher concentrations and Should you have any questions about the Benzyl Alcohol monograph, please contact Dr. Tong (Jenny) Liu (240-221-2072 or jyl@usp.org ). 108.15 . MATERIAL SAFETY DATA SHEET Page 1 of 7 BENZYLALCOHOL-DHA 1. RTECS # DN3150000 CAS # 100-51-6 See: NMAM or OSHA Methods. . PB85141216. Have approved eyewash facility, safety shower, and fire extinguishers readily available. This preservative has a wide safety margin and can be integrated into a variety of products. The Cosmetic Ingredient Review Expert Panel previously established concentration limits for benzyl alcohol, benzoic acid, and sodium benzoate in cosmetics and determined that the available data were insufficient to support the safety of these ingredients during inhalation exposure. . Heatingto decomposition may release carbon monoxide and other toxic vapors. Int. We have completed the draft assessment of benzyl alcohol. Join Fema Today Learn . Cetearyl alcohol, cetyl alcohol, isostearyl alcohol, myristyl alcohol, and stearyl alcohol are commonly used fatty acids in skincare References: CIR, 1988. For any questions about the PDG and its processes, please see the Pharmacopeial . Used in various industrial applications such as paints and coatings, sealants and adhesives, elastomers, floor . Benzyl ethyl ether. benzyl alcohol preservative neonates. 2001; 20 (Suppl 3):23-50. Benzyl alcohol. Benzyl Benzoate is an ester of Benzyl Alcohol and Benzoic Acid. OSHA Occupational Chemical Database BENZYL ALCOHOL Label abbreviations descriptions BENZYL ALCOHOL * All sampling instructions above are recommended guidelines for OSHA Compliance Safety and Health Officers (CSHOs), please see the corresponding OSHA method reference for complete details. Benzyl alcohol was evaluated by JECFA in 1980 (JECFA, 1980) and concluded a group acceptable daily intake (ADI) (for benzoic acid together with benzyl alcohol) of 0-5 mg/kg body weight (bw), subsequently agreed by the Scientific Committee for Food (SCF) in 2002. benzaldehyde content < 0.05 %). Safety not established in patients >60 years of age. In 1982, two groups of investigators independently concluded that intravascular infusion or flush solutions containing benzyl alcohol, 0.9% caused severe metabolic acidosis, encephalopathy, and. Its IUPAC name is phenyl methanol. Studies have revealed that repeated exposure can lead to contact dermatitis. PMID 28450044; DOI 10.1016/j.yexcr.2017.04.025; Experimental cell research 2017 08; 357 (1):67-78. Benzyl alcohol is an aromatic alcohol, a naturally occurring clear liquid produced by plants such as jasmine, and features in a wide variety of household products, cosmetics and foods, including. Benzoic Acid is an aromatic acid used in a wide variety of cosmetics as a pH adjuster and preservative. Benzyl alcohol 99.6 100-51-6 Dibenzyl Ether 0.1 103-50-4 Ingredient name % CAS number There are no additional ingredients present which, within the current knowledge of the supplier and in the concentrations applicable, are classified as hazardous to health and hence require reporting in this section. The limited body exposure, the duration of use, and the frequency of use were considered in concluding that the nonimmunologic reactions would not be a concern. More Information. material safety data sheet (MSDS) for benzyl alcohol before handling. Wash Material Safety Data Sheet Benzyl alcohol MSDS Section 1: Chemical Product and Company Identification Product Name: Benzyl alcohol Catalog Codes: 10290,20290,30290,50290,70290 CAS#: 100-51-6 RTECS: DN3150000 TSCA: TSCA 8(b) inventory: Benzyl alcohol CI#: Not applicable. Save Print. 1,2-Dibenzyloxyethane. General Description A clear colorless liquid with a pleasant odor. Benzyl alcohol was administered by oral gavage daily to groups of 10 male and 10 female rat pups from post natal day 22 for a period of 6 weeks. These are all ingredients that are widely used in skincare products. Antioxidants used in pharmaceutical products include butyl. BENZYL ALCOHOL, NF/FCC. GHS07. Reactivity Alerts none Air & Water Reactions Skin ContactWash off immediately with plenty of water for at least 15 minutes. When prescribing AquaMEPHYTON in infants, consider the combined daily metabolic load of benzyl alcohol from all sources including AquaMEPHYTON (contains 9 mg of benzyl alcohol per mL) and other drugs containing benzyl alcohol. The minimum amount of benzyl alcohol at which serious adverse reactions may occur is not known. Benzyl chloride. More Information; gpi: N/A: Dose-levels of 100, 300 and 600 mg/kg/day were selected on the basis of published data. Hazard Statements. The 'Substance identity' section is calculated from substance identification information from all ECHA databases. 2,4-Dichlorophenetole. Signal Word. If not breathing give artificial respiration Consult a physician. Benzyl alcohol has moderate solubility in water (4 g/100 mL) and is miscible in alcohols and diethyl ether. EPA TSCA Section 8(d) unpublished health/safety studies: EPA TSCA TEST SUBMISSION (TSCATS) DATA BASE, JANUARY 2001: Control animals received vehicle only (distilled water). Safety Data Sheets . 2 28-9899-01 AC Precautions Benzyl alcohol is only partially soluble in water, approximately 4 g/100 mL at room temperature. how to paint stainless steel to black; full spectrum led grow lights for sale; melitta caffeo solo troubleshooting It includes updated information for the package leaflet and needs to be read in conjunction with the background scientific . Benzyl Alcohol is metabolized to Benzoic Acid, which reacts with glycine and excreted as hippuric acid in the human . BENZYL ALCOHOL, NF/FCC. Benzyl Alcohol Special Grade Emprove Expert is an extraordinarily pure product with impurity specification thresholds even below current requirements of designated pharmacopoeias (e.g. Some substance identifiers may have been claimed confidential, or may . J. Toxicol. Isophorone. Isopropyl-2,4,5 . Updated. The CIR Expert Panel evaluated the scientific data and concluded that these ingredients were safe for use in cosmetic products. of benzyl alcohol toxicity in newborns [33]. Intravenous formulations of some corticosteroids (betamethasone and triamcinolone) contain benzyl alcohol, contraindicated in newborns as it can induce anaphylactic reactions under 3 years of life [34] and the routine use of continuous infusions of benzodiazepines, including midazolam, in this Related Pages. Sodium Benzoate is the sodium salt of Benzoic Acid used as a preservative, also in a wide range of cosmetic product types. Show this safety data sheet to the doctor in attendance.Move out of dangerous area. Benzyl salicylate is an ester, a chemical compound derived from an acid. Top medications with this excipient, Cetirizine Hydrochloride (chewable) 10 mg, Benzyl alcohol 100-51-6 202-859-9 603-057-00-5 - 4. It's also called an "aromatic alcohol," and is used as a preservative, as a fragrance ingredient, as the active ingredient in head lice treatment, and as a solvent, which simply means that it's used to dissolve other ingredients to make a smooth formula or solution. Benzyl alcohol, an aromatic alcohol characterized by its polarity, relatively low toxicity and low vapor pressure, serves as a useful solvent for a variety of industrial applications. 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